PrEP (Pre-Exposure Prophylaxis) and PEP (Post-Exposure Prophylaxis) are both antiretroviral medications used to prevent the transmission of HIV. However, they are used in different situations and time frames. PREP medication is taken daily by individuals at a higher risk of exposure to HIV to reduce the likelihood of acquiring the virus. It’s best to start taking PrEP several days before potential exposure and to continue taking it regularly to maintain protection.

On the other hand, PEP is taken after a potential exposure to HIV and must be started within 72 hours of exposure. The goal of PEP is to prevent the virus from establishing a permanent infection in the body. Both PREP and PEP are highly effective when taken consistently and as prescribed, but they are not 100% effective and should be used in conjunction with other safe sex practices.